Although the ancient Cross of the township has not survived, it presumably occupied the site on the high ground at the junction of Dragon Lane and Cross Lane (formerly Stank Lane). This area became historically known as Whiston Cross.
The consecration of the parish church of St. Nicholas took place 30th July 1868 on a site purchased and given by the then vicar of Huyton, the Rev. Ellis Ashton. The road on which it stands was originally called Tarbock Road but is now known as Windy Arbor Road. The following year in June 1869, part of the Whiston township together with part of the township of Tarbock, was formed into its own parish. The formation of the Whiston Rural District Council in 1874 brought about greater control of local affairs which had previously been dealt with by governing bodies in Prescot.